Original Articles
Comparison Of Effect Of Two Different Doses Of Succinylcholine On Neuromuscular Blockade In Patients Undergoing Laparoscopic Surgeries Under General Anaesthesia | |
Alaksh Kher, Pooja Bihani, Ankit Vyas, Caren C. Selvin, Mathura L. Tak | |
Aim: To compare effect of two different doses of succinylcholine on neuromuscular blockade in patients undergoing laparoscopic surgeries under general anaesthesia. Methods: Total 56 patients belonging to ASA PS class I and II, who were undergoing elective laparoscopic surgery under general anaesthesia between ages 18 to 60 years old, were randomly allocated into either succinylcholine at 1 mg/kg BW (Group A) or succinylcholine at 1.5mg/kg BW (Group B).We assessed the duration of neuromuscular blockade, hemodynamic parameters, postoperative complications and anaesthetic variables between both groups. Results: The duration of neuromuscular blockade was also less in group A than group B (6.89±0.68 seconds and 8.42±0.83 seconds respectively) (p=<0.01). The hemodynamic responses and Post-operative Complications in both doses were found to be comparable. Conclusion: The duration of neuromuscular blockade was also found to be lesser when patients were given succinylcholine at 1mg/kg BW in comparison with 1.5 mg/kg BW, also indicating a dose dependent response. The hemodynamic responses were found to be comparable. Therefore, we would like to conclude by saying that succinylcholine can be safely used to perform endotracheal intubation at both 1mg/kg and 1.5 mg/kg BW doses, with 1 mg/kg BW being a safer and better dose |
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