Background: Post-mortem identification, a forensic procedure, is difficult to perform and it is obligatory in terms of the law and social norms. The present study assessed sex identification using the maxillary sinus. Materials & Methods: 90 healthy individuals without any pathology in the sinus above 20 years of age of either gender were subjected to CBCT scan using Vatech machine. The maxillary sinuses on the left and right were measured superoinferiorly in the coronal section and mediolaterally in the axial section in millimeter at the maximum dimension. The volumetric analysis of the maxillary sinus was done in a cubic centimeter (cm[3]) in the sagittal section. Results: Out of 90 patients, 50 were males and 40 were females. Supero- inferior measurement of right maxillary sinus was 37.4 mm in males and 33.2 mm in females. Supero- inferior measurement of left maxillary sinus was 38.1 mm in males and 33.8 mm in females. Medio- lateral measurement of right maxillary sinus was 33.5 mm in males and 31.9 mm in females. Medio- lateral measurement of left maxillary sinus was 33.2 mm in males and 31.4 mm in females. Volume of right maxillary sinus was 17.2 mm in males and 13.6 mm in females. Volume of left maxillary sinus was 16.9 mm in males and 13.5 mm in females. The difference was significant (P< 0.05). % of males and % of females correctly classified in relation to right SI (mm) was 70% and 57.6%, left SI (mm) was 81% and 58.3%, right ML (mm) was 65% and 52%, left ML (mm) was 58% and 54%, right volume (cm3) was 78.4% and 57% and left volume (cm3) was 75% and 59% respectively. The difference was significant (P< 0.05). Conclusion: Sex identification by analyzing the skeletal remains is instrumental in forensic investigations. Maxillary sinus measurements showed better predictability values in males as compared to females in the case of superoinferior measurement of left maxillary sinus and volume of the right maxillary sinus.