Background: Prostate cancer (PCa) ranks second in terms of cancer-related deaths among males. Since PCa tumors often grow slowly, a significant number of men (>2.9 million men in the US) are affected by this cancer, which translates into a high disease burden.The present study was conducted to assess role of Magnetic resonance imaging in detection of prostate cancer. Materials &Methods: 46 cases of prostate cancer in males underwent MRI. Diffusion-weighted imaging (DWI) sequences: b values of 0, 500, 1,000, and 3,000 s/mm2, slice thickness of 3 mm, TR of 3,100 ms, and TE of 102 ms, a gradient-echo T1-weighted sequence in axial planes was used to create dynamic contrast-enhanced (DCE) magnetic resonance imaging. Results: Age group 20-40 years had 6, 40-60 years had 19 and 60-80 years had 21 patients. The difference was significant (P< 0.05).Gleason grading was indolent well-differentiated tumour seen in 24, intermediate risk in 15 and clinically aggressive in 7 cases. The difference was significant (P< 0.05).MRI sequences T2w showed sensitivity, specificity, PPV, NPV, accuracy and AUC of 69, 76, 90, 63, 79 and 0.76. T2w+ DCE showed 72, 83, 92, 67, 88 and 0.87. T2w+ DWI showed 75, 87, 96, 71, 92 and 0.85. DWI+DCE showed 87, 91, 97, 74, 91 and 0.94 and T2w+ DCE+ DWI showed 90, 96, 98, 81, 94 and 0.95 respectively. Conclusion: When it comes to detecting prostate cancer in males, magnetic resonance imaging (MRI) offers excellent sensitivity, specificity, PPV, NPV, accuracy, and AUC.