In this article, we recorded the length and width of pterygopalatine fossa and its morphological variations using CBCT images. Being familiar with its anatomy on advance radiolographic modality such as CBCT will overcome diagnostic and surgical difficulties. Type II pterygopalatine fossa was most commonly seen males and females (53% and 58 %). There was a significant difference found in type I and Type III between genders. The mean widths of pterygopalatine fossa at various heights (upper (A) middle (B) and lower third (C)) were calculated in both the gender and sides but the results were statistically insignificant. A detailed anatomy of pterygopalatine fossa on CBCT helps to make diagnostic as well as surgical procedures possible as these are complex anatomical structures.