Aim: The present study aimed to evaluate the levels of total immunoglobulin E and the percentage count of eosinophils in patients with allergic diseases. Methods: This study was carried out at a tertiary care hospital for the period of 1 year, and 200 patients with allergic disease were classified into three groups (72 Asthma, 45 Rhinitis, and 83 Urticaria) and 100 individuals as a healthy control. Results: Patients with asthma, allergic rhinitis, and urticarial had significantly higher mean total blood IgE levels (p<0.01) compared to healthy controls (25.65 ± 5.75 IU/ml). Patients aged 30-39 with allergic asthma, rhinitis, and urticaria had significantly higher mean serum levels of T-IgE (P<0.05) compared to healthy controls (42.05 ± 17.43 pg/ml). Patients showed a substantial (p<0.05) rise in mean serum T-IgE across genders compared to healthy controls. Patients with allergic asthma, rhinitis, and urticaria had significantly higher eosinophil counts (4.36 ± 0.54%, 4.37 ± 0.52%, and 4.16 ± 0.45%) compared to healthy controls (2.56 ± 0.84%). Conclusion: The research observed elevated T-IgE and eosinophil counts in allergic disease serum. All allergic patients of all ages had significantly higher total IgE levels than healthy controls. Male and female T-IgE concentrations vary by allergic illness. Allergic asthma, rhinitis, and urticaria patients had a considerable rise in eosinophil percentage.