Background and Aim: Family Accommodation is an important however seldomly addressed aspect of Obsessive-Compulsive Disorder. Studies worldwide have shown that Higher Family Accommodation is related to Higher Severity of OCD and Morbidity. In this study we aim to understand the factors associated with Family Accommodation and Disease Severity in Female patients of Obsessive-Compulsive Disorder. Methods: A cross-sectional observational study done in 36 Female Patients presenting to Outpatient Department of Psychiatry Department in a Tertiary Care Centre of Central India, during a period of Sept-2022 to Feb-2024.Patients were assessed for Socio-Demographic and Clinical Variables using Semi-Structured Proforma, Yale Brown Obsessive Compulsive Scale (YBOCS), Family Accommodation Scale – Patient Version (FAS-PV), Clinical Global Impressions – Severity Scale (CGI-S) and Clinician Rating Scale (CRS) for Treatment Adherence. Statistical Analysis: Summary Statistics, t-test, ANOVA, Correlation and Regression analysis were applied and presented. Result: Higher Family Accommodation Scores were related to Higher Severity of OCD, Higher Impairment in Global Functioning, Poorer Treatment Adherence and Poorer Insight. Education, Socio-Economic Status and Family’s Attitude also contribute towards Family Accommodation in these patients. Conclusion: Family Accommodation was positively correlated with Severity of OCD and Global Impairment in Patient’s Functioning. These findings pave the way for better involvement of Patient’s Family in order to decrease the burden of illness and distress faced by patients and their family members.