Background:Diabetic foot is one of the most mutilating and severe complications of diabetes, the prevalence of which is gradually increasing over the past decade. This study was conducted for the evaluation of diabetic foot patients undergoing surgical treatment.Materials and Methods:This retrospective cohort study examined 100 diabetic foot ulcer (DFU) patients who underwent surgical intervention, categorized into two groups: the Enhanced Recovery After Surgery (ERAS) group, which included 50 patients, and the non-ERAS group, also consisting of 50 patients. All surgeries were standardized and performed by the same team. Results:In this study there were 50 subjects in ERAS group and 50 subjects in non-ERAS group.The length of stay (LOS) was 13.69 ± 5.2 in ERAS group and 28.5 ± 8.6 in the non-ERAS group. The expenses were found to be less in the ERAS group while more in the non-ERAS group. Conclusion:The findings from the comparison of the ERAS and non-ERAS groups indicate that the implementation of the ERAS protocol may enhance the quality of medical care and effectiveness. This improvement is evidenced by increased patient satisfaction, higher scores on the activities of daily living scale, a reduction in length of stay (LOS), and a decrease in overall hospital costs.