Background: Oral Submucous Fibrosis (OSMF) is one of the potentially premalignant disorder which is irreversible in nature. Primary etiology seems to be areca nut and gutkha chewing. The main concern in this is the management of trismus and burning sensation of the oral mucosa. Aims: Assessment of demographic profile, risk factors and clinical presentation of OSMF in central Indian patients attending ENT OPD. Material and Methods: This cross sectional observational study was carried out in the ENT department. A total of 150 attending our OPD were enrolled. Patient’s clinico-demographic data, details of chewing habits, including frequency and duration of chewing habits was collected. Clinical staging was done on the basis of palpable fibrous bands. Functional staging was accomplished by measuring mouth opening. Result: The Majority (66.6%) of the OSMF cases were 21-40 years age group, predominantly males (74.7%). Most of the OSMF cases (46.7%) had a low socioeconomic status and half of them were under graduate There was a statistically significant increase for areca nut chewing, gutkha chewing, tobacco chewing, smoking habits and alcohol (P < 0.05) in males when compared with females. Burning sensation in mouth and reduced mouth opening were the most common clinical finding of OSMF. The maximum patients were seen in stage II (37%) followed by stage III (34%), Severity of OSMF was more in subjects who had the habits for longer duration. Conclusion: Patient’s education, socioeconomic status and chewing habit variables (duration & frequency) had significantly correlated with the clinical features and severity of the OSMF.