Background and Aim: Mild to severe complication are typically expected and seen in the post-operative phase of mandibular third molar surgeries. However, timely identifications and precise management of these dilemmas can minimize patient problems and discomfort. Therefore this study was designed and conducted assess various clinical parameters pertaining to mandibular impacted third molar surgery. Materials & Methods: Total 50 patients were selected by simple random sampling procedure wherein both male and female patients were included in the study in the age range of 25 years to 40 years. Different clinical parameters were asked in post-operative phase like pain, swelling, inflammation, discharge, trismus, weakness. A questionnaire containing 6 questions were given to the patients in their one week follow-up period of mandibular impacted third molar surgery. Written and signed informed consent was obtained from all participating patients individually. P value less than 0.05 was considered as significant. Statistical Analysis and Results: Statistical analysis was completed by SPSS software. Total 30 male and 20 female patients were studied in detail for their responses. 18 patients agreed that they had sense of pain after the surgery (1 week). Total 38 patients complaint of swelling in the operated area (1 week). 30 patients showed the signs of inflammation in the nearby areas 1 week). P value was highly significant for question number 4, 5 and 6. They were 0.010, 0.001 and 0.002 respectively for last three questions. ANOVA analysis for between questions, within questions and cumulative revealed highly significant p value (0.002). Conclusion: Authors concluded that some complications have been extensively reported by most of the patients like swelling of surgical site, difficulty in mouth opening/trismus and general body weakness. Hence, post-operative recall follow-up is of greatest importance in mandibular third molar impaction surgeries. Authors also expect other long term future studies with larger sample and comprehensive analysis.