Background: Headache is a common and disabling symptom with a high prevalence in the population. It is also among the most prevalent complaints in patients presenting to the emergency department. In this study, we correlated role of CT scan in the etiology of various types of Headache. CT scan play extremely crucial role in the etiology of Headache. Sometimes the headache of a small proporation of patients results from serious intracranial disorders such as tumors or intracranial hemorrhage. Materials and Methods: A retrospective study was conducted among 201 patients of headache, soft tissue window and bone algorithms with wide window settings was studied to visualize any positive results for headaches and the gathered Data was analyzed using Statistical Package for the Social Science (SPSS) software. Results: The typical age for headache cases underwent to CT scan was the age above 60 years old which constituted (24%) of total cases. The most common associated symptom of headache underwent to CT scan is dizziness which constituted 52% of total cases. 131 out of 201 cases are associated with normal CT scan appearance (65.17) and 70 out of 201 cases are associated with abnormal CT scan appearance (34.83%). The most common positive findings are brain involutional changes where 25 (12.5%) of cases had brain involutional changes followed by ischemia by 18 (9%) of cases. Age groups are significantly correlated with CT findings (P value < 0.05). The majority of CT abnormal findings were found in the age group above 60 years old. Conclusion: The majority of CT abnormal findings were found in the age group above 60 years old taking into consideration most of the positive findings may be considered normal for age. CT scan for headache cases is a useful screening modality either to identify or rule out structural abnormalities.