Background: Ropivacaine is structurally related to bupivacaine but less toxic, is preferred for its favourable sensory and motor block profiles. The present study was conducted to compare clinical efficacy of isobaric ropivacaine versus hyperbaric ropivacaine in patients posted for lower limb surgeries. Materials & Methods: 60 patients of ASA I & II between the age of 18 to 65 years of either gender undergoing lower limb surgeries were randomly divided into 2 groups by close envelope method. Group Hr (n=30) – to receive 3ml 0.75% Hyperbaric Ropivacaine + 0.5ml Fentanyl (25mcg). Group Ir (n=30) – to receive 3ml 0.75% Isobaric Ropivacaine + 0.5ml Fentanyl (25mcg). Results: In group I, males were 16 and females were 14. In group II, males were 17 and females were 13. There was non- significant difference in anthropometric parameters and pre-operative vitals between both groups. The mean onset of sensory block was significantly (p=0.001) lower amongpatients of Hr (3.57 ± 0.67 minutes) compared to Ir (4.90 ± 0.71 minutes). The mean onset of motor blockade was significantly (p=0.001) lower among patients of Hr (7.17±1.17 minutes) compared to Ir (9.57±0.81 minutes). T8 was achieved in 53.3% patients of Hr group and in 10% patients of Ir group. However, T10 was achieved among 46.7% patients of Hr group and in 33.3% patients of Ir group. There was significant (p=0.001) difference in maximum level of block achieved between the groups. The mean duration of surgery was insignificantly (p>0.05) lower among patients of Hr (85.17±20.61 minutes) than Ir (90.17±19.27 minutes). The mean total duration of sensory block was significantly (p=0.001) lower among patients of Hr (163.50±9.57 minutes) compared to Ir (187.67±8.88 minutes). The mean total duration of post operative analgesia was significantly (p=0.001) lower among patients of Hr (212.17±10.80 minutes) compared to Ir (230.67±12.22 minutes). The difference was significant (P< 0.05). Complications such as bradycardia and hypotension was present in 4 (13.3%) in Hr and 1 (3.335) in Ir group. The difference was significant (P< 0.05). Conclusion: Hyperbaric ropivacaine has early and faster onset, spreads more to higher levels and is early to regress while Isobaric ropivacaine has longer duration of action, longer duration of post-operative analgesia and better VAS score.