Background: The word for inflammations of the cornea is keratitis. Infections of the cornea are recognized as the second leading cause of monocular blindness in the world, ranking behind untreated cataract surgery, especially in impoverished countries and tropical regions generally. The present study was conducted to assess cases of infective keratitis. Materials & Methods: 52 patients of infective keratitis of both genders were selected and diagnosed using slit-lamp biomicroscope. Scrapings underwent bacterial and fungal pathogen culture, Gram staining, and potassium hydroxide preparation. Results: Out of 52 patients, males were 32 and females were 20. Micro-organisms for corneal ulcers were bacterial isolates in 26, fungal growth in 14 and no organism isolated in 12 cases. The difference was significant (P< 0.05). Bacterial isolates were Micrococcus in 6, staphylococcus aureus in 10, coagulase-negative staphylococci in 3, Klebsiella spp. in 4 and Pseudomonas spp. in 3 cases. Fungus found to be fusarium spp. in 3, unidentified in 2, candida spp. in 6, curvularia spp. in 2, and aspergillus spp. in 1 case. The difference was significant (P< 0.05). Conclusion: Candida species, coagulase-negative staphylococci, and staphylococcus aureus. were the pathogens most frequently implicated in infective keratitis.