Background: One of the most difficult public health issues facing the globe today is corneal blindness, which is a major source of visual impairment in poor nations like India. The present study was conducted to assess outcome in patients undergoing penetrating keratoplasty. Materials & Methods: 90 patients undergoing penetrating keratoplasty of both genders were selected. A thorough visual examination was performed using a slit lamp and torch light, and the results were noted. Every patient had a postoperative examination, treatment, and documentation of any difficulties. Results: Visual acuity 1-0.5 had 0 pre-operatively and 5 post- operatively, 0.3-0.16 had 0 pre-operatively and 40 post- operatively, 0.1-0.016 had 46 pre-operatively and 24 post- operatively and CT to PL had 44 pre-operatively and 21 post- operatively. The difference was significant (P<0.05). Common pathologies were adherant leucoma in 26 and bullous keratopathy in 12 cases, corneal ulcer in 7, keratomalacia in 5, anterior staphyloma in 3 cases, Leucomatous opacity in 22, chemical injuryin 6, and graft rejection in 9 cases. Common complications were raised OP in 2, mild AC reaction in 5, rejection in 1, epithelial defect in 3, and wound leak in 2 cases. The difference was significant (P< 0.05). Conclusion: Patients with corneal blindness were reported to respond better to penetrating keratoplasty.