Original Articles
Endometrial pattern among female patients with dysfunctional uterine bleeding | |
Dr. Kuldeep Singh, Dr. Savita Singh, Dr. Suman Lata Verma | |
Background: As dysfunctional uterine bleeding (DUB) produces significant morbidity and interferes with everyday activities, it is one of the most prevalent problems in females that can arise at any point throughout the reproductive cycle and about 20% of affected patients seek consultation. For proper treatment, endometrial histology must be evaluated in patients with DUB, so the present study was carried with the aim to assess the endometrial pattern among female patients with dysfunctional uterine bleeding (DUB). Methods: The present cross-sectional study was carried out among 264 female patients with dysfunctional uterine bleeding of at least six months under the Department of Pathology, GSVM Medical College, Agra for a period of 1 year. The endometrial biopsy sample was taken from diagnostic dilatation and curettage (DNC) or hysterectomy and biopsy sample was received in our department.The pretested proforma was used to collect the patients details such as age, BMI, parity, presenting complaints and endometrial pattern of biopsies. The collected data was entered in the MS excel spreadsheet and analysed using the same. Results: In our study, 62.1% of patients were >40 years of age, and 12.8% of patients were having age >50 years. The mean age of the patients was 42.86±12.73 years. The mean BMI of the patients was 24.81±5.34kg/m2.Biopsy of patients showed most common endometrial pattern were Proliferative endometrium (22.0%), Irregular maturation (19.7%), simple hyperplasia (23.5%) and Endometritis (11.7%)In perimenopausal group simple hyperplasia (30.3%) was the most common endometrial pattern followed by proliferative endometrium (21.2%) and irregular maturation (16.7%). Among postmenopausal group atrophic endometrium (26.6%) was the most common endometrial pattern followed by simple hyperplasia (23.5%); complex hyperplasia without atypia (23.5%) and malignancy (17.6%). Conclusion: Histopathological examination of D& C tissuein patients of abnormal uterine bleeding shows a wide spectrum of changes ranging from normal endometrium to malignancy, however, frequency of cause varies with age. |
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