Background:The sciatic nerve, which originates from the lumbosacral region, is the biggest nerve in the human body. It is composed of five nerve roots (L4-S3). The present study was conducted to assess variations of the sciatic nerve. Materials & Methods:60 formalin fixed cadavers were selected and The Beaton and Anson classification system was used to classify anatomic variations. Divisions of sciatic nerve division was also recorded. Results: Type 1 was seen in 47, type 2 in 3, type 3 in 4, type 4 in 1 and type 5 in 3 and type 6 in 2 cases. The difference was significant (P< 0.05).The level of division of sciatic nerve was at D1 in 20, at D2 in 4, at D3 in 3, at D4 in 32 and at D5 in 1 case. The difference was significant (P< 0.05). Conclusion: The location, branching, and distribution of the sciatic nerve have clinical significance. The sciatic nerve's long route makes it vulnerable to injury, which is why it is commonly utilized in common medical operations like anesthesia, rehabilitation, orthopaedics, and neurology.