Original Articles
To determine the frequency of thyroid impairment in individuals with metabolic syndrome | |
Dr. Gaurav Runwal, Dr. Jitendra Chouhan, Dr. Prashant Jain | |
Aim: To Determine the frequency of thyroid impairment in individuals with metabolic syndrome. Materials and Methods: It comprised a total of 100 patients who were matched for age and sex (50 cases and 50 controls). Patients exhibiting central adiposity, defined as a waist circumference of 90 cm or more in males and 80 cm or more in females, together with serum triglyceride levels of 150 mg/dl or more, serum HDL cholesterol levels below 40 mg/dl in men and below 50 mg/dl in women, and abnormal blood pressure: This research comprised individuals with a systolic blood pressure of 130 mmHg or higher, or a diastolic blood pressure of 85 mmHg or higher, as well as a fasting plasma glucose concentration of 100 mg/dl or higher.Cases: Subjects fulfilling the criteria for MetS were included as cases.Controls: Apparently normal and healthy subjects without MetS were considered as controls. Results:The average T3 level in male controls was 1.45±0.86, whereas in cases it was 1.65±0.84. However, this difference is not statistically significant (p=0.13). The average T3 level in female controls was 1.77±2.21, whereas in cases it was 1.83±0.13. However, the difference between the two groups is not statistically significant (p = 0.24). The average T4 level in male controls was 10.03±2.58, whereas in cases it was 9.05±3.12. However, this difference is not statistically significant (p = 0.21). The average T4 level in female controls was 10.04±2.01, but in cases it was 9.14±1.76. However, this difference is not statistically significant (p = 0.31). The average TSH level in male controls was 1.76±2.33, whereas in cases it was 4.52±4.11, showing a statistically significant difference (p=0.03). The average TSH level in female controls was 2.11±2.47, but in cases it was 7.23±8.88, showing a statistically significant difference (p = 0.04). The tables are labeled as Table 1 and Table 2. Conclusions: Thyroid dysfunction, namely subclinicalhypothyroidism, is prevalent in individuals with metabolic syndrome and is linked to some aspects of metabolic syndrome. |
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