Background:Neonatal seizures constitute a common neurological emergency and they are often the first sign of neurological dysfunction. Neonatal seizure is associated with a high risk of mortality as well as neurological impairment/epilepsy disorders in later life. Common causes include hypoxic-ischemic encephalopathy, intracranial hemorrhage, meningitis, hypoglycemia, hypocalcemia, other metabolic disturbances etc.Methods:We conducted this observational study in NICU of NMCH, Patna over 2-year duration from June 2019 to May 2021 including term neonates of less than 1 month age with seizure and who stayed for >24 hours. Parameters studied were demographic profile, etiology, type of seizure, time of onset of seizure & short-term outcome.Result:Of the 104 neonates studied, male: female ratio was 1.27:1. Mean GA was 39.2 ±1.4 weeks and mean admission weight was 3.06±0.63 Kg. Perinatal asphyxia was the commonest risk factor (47.1%) followed by septicemia-meningitis (30.8%) and metabolic disturbances (hypoglycemia, hyponatremia, hypocalcemia) in 31.7%. Subtle seizure was the commonest seizure type (29.5%) followed by focal clonic seizures (26.6%) whereas tonic seizures were the least common (10.1%). 74.8% of the events were reported before 72 hours of age and the rest 25.2% were reported after 72 hours of age. In neonates with seizure, mortality was 29.8%, mean duration of hospital stay was 9.7±2.8 days. There was a significant increase in duration of hospital stay and delay in commencement of oral feeds, but there was no significant increase in mortality, need of ventilator support or inotrope support in such neonates as compared to term neonates without seizures.Conclusion:HIE and sepsis-meningitis was accountable for approximately 75% of total neonatal seizure cases. Subtle seizures were the commonest clinical type of seizure which was closely followed by focal clonic seizure. Most of the neonates developed seizure within 72 hours of life. Occurrence of seizure in term neonate seems to significantly increase duration of hospital stay and delay the commencement of oral feeds without increasing mortality.