Background: The study was conducted to assess the levels of serum potassium in patients with acute myocardial infarction. Material and methods: In this study there were 100 subjects. The serum potassium levels had been measured in the subjects having myocardial infarction and those who did not have the condition. 50 subjects had myocardial infarction and 50 subjects were controls. Serum potassium levels were evaluated. Statistical analysis had been conducted using SPSS software. Results: It was observed that serum potassium levels in subjects having AMI were reduced (3.14 mmol/L) as compared to the subjects in control group (4.13 mmol/L). Conclusion: It was concluded from the results that serum potassium concentrations among subjects having AMI were reduced as compared to the controls.