Aim:To determine the significance of lipid profile in individuals diagnosed with non-alcoholic fatty liver disease. Material and methods: Our department conducted a sonographic evaluation of 100 patients, consisting of 40 males and 60 females, to assess the presence of fatty liver. Only patients aged 18 years or older who were identified with nonalcoholic fatty liver by ultrasonography were included in the research, after the patient's informed permission. Subjects were classified as cases if they met the standard criteria for fatty liver, as accepted by the American Gastroenterology Association. Results: Ultrasonography revealed that 47% of cases had grade I NAFLD, 43% had grade II NAFLD, and 10% had grade III NAFLD. out of 100 patients, 34 were asymptomatic while the remaining 66 patients were symptomatic. 56% of patients had upper abdominal discomfort, whereas 53% of patients reported weariness.Triglyceride levels in the serum, as well as total cholesterol, LDL, and VLDL levels, were elevated in 67%, 46%, 34%, and 26% of patients, respectively. 63% of patients had low serum HDL values. Significance was attributed to P values less than 0.05. The study found a significant correlation between higher grades of NAFLD and higher levels of blood total cholesterol (P value-0.002), LDL (P value-0.001), and VLDL (P value-0.004), as well as lower levels of HDL (P value-0.001). There was no significant correlation seen between blood triglyceride levels (P value-0.05) and the progression of non-alcoholic fatty liver disease (NAFLD) as determined by sonographic diagnosis. Conclusion:The majority of individuals with non-alcoholic fatty liver disease (NAFLD) in India are asymptomatic, without diabetes or hypertension. While liver biopsy is considered the most reliable way for diagnosing NAFLD, Ultrasonography, a non-invasive and straightforward instrument, may be used to diagnose NAFLD at an early stage in asymptomatic individuals.