Background: In recent years, a number of factors have been under consideration as possible influences on the rising cesarean rate. General anaesthetics (GAs) have been in use since the mid-19th century. Spinal anesthesia is a simple technique that provides a deep and fast surgical block through the injection of small doses of local anesthetic solution into the subarachnoid space. Hence, the present study was conducted to compare the effect of general and spinal anesthesia on renal functions and hemodynamic profile among patients undergoing cesarean section. Materials &Methods:100 patients scheduled to undergo cesarean section were enrolled. A Performa was made and complete demographic and clinical details of all the patients was obtained. All the patients were randomized into two study groups: Group A: Spinal anesthesia group, and Group B: General anesthesia group. All the patients underwent cesarean Section according to anesthesia of their respective study groups. Blood samples were obtained preoperatively, and postoperative and renal profile was evaluated and compared. The hemodynamic profile was monitored at regular intervals and was compared among the two study groups. Results:Mean age of the patients of group A and group B was 43.5 years and 40.8 years respectively. Majority proportion of patients of both the study groups were males. The hemodynamic profile showed a significant variation among patients of group A in comparison to patients of group B. However, while comparing the renal profile among patients of the two study groups, non-significant results were obtained. Conclusion:Both general and spinal anesthesia didn’t alterrenal profile; however, spinal anesthesia had significant effect on hemodynamic profile in comparison to general anesthesia.