Liver is the largest solid organ in the body and has manyfunctions in the body. It gets involved by many diseases, some of these presents with clinical symptoms and signs while some are diagnosed only on autopsy. Aim- To study thehistopathological spectrum of liver including neoplastic lesions related or unrelated to cause of death in autopsy cases. Material and methods- This was a descriptive study done in the department of pathology Government Medical College Jammu from year 2020 to2023. Result-Out of 300 cases studied, males were the most common with 270 cases ( 90%),females were 30 cases only (10%). The male to female ratio was 9:1. Maximum number of cases were recorded between age group of 40-49 years of age group and the least number of cases were seen in age group >70 years. Most common cause of death was found to be road traffic accidents(22%) followed by hanging (16%), sudden death(14.7%), poisoning(11.3%), drowning(10%), unknown cause(7.7%), natural cause(6.3%), hospital death(5.3%), custodial death(4%),electrocution(2.7%) . Majority of the specimens were within normal histological limits( 28%); followed by fatty change(25 %),autolysed specimen( 13.7%) , chronic venous congestion( 10.7%), steatohepatitis(9.5%),cirrhosis(5 %), tuberculosis(1.8%), Malaria( 0.3%). Conclusion-Silent diseases of liver are not uncommon .Histopathological examination of autopsy cases aids in identifying these such as fatty change,chronic venous congestion,cirrhosis andeven in infectious disease cases like malaria and tuberculosis.Thus providing an insight into the true prevalence of these diseases or lesions.