Background: Diabetic foot ulcers (DFUs) represent a significant complication of diabetes, leading to severe outcomes including amputation. Management strategies are pivotal in preventing such severe consequences. Objective: To compare the efficacy and outcomes of surgical versus non-surgical interventions in the treatment of diabetic foot ulcers. Methods: This cross-sectional study involved 200 patients with DFUs, divided equally into surgical and non-surgical treatment groups. We collected data retrospectively from medical records from 2019 to 2022. Results: We assessed wound healing rates, time to healing, and recurrence rates, analyzed using chi-square tests and independent t-tests. Conclusion: The findings will provide insights into the comparative effectiveness of treatment modalities, aiding in optimal strategy selection for DFUs.