Background:Various risk factors have been recorded which prolong the QTc interval, like an increasing age, female gender, genetic variants, cardiovascular diseases and electrolyte disturbances. The present study was conducted to assess risk factors that causeQTc prolongation.Material & methods:Patient’s relevant data required for this study was obtainedfrom the patient’s medical record. The QTc was calculated, measured and analysed. The various Biochemical test were observed to find out any comorbidity/acquired cause of QTc prolongation in the patients. All the collected data was analysed statistically using SPSS version 21 software.Results:QTc prolonged among 9 subjects. Total 10 subjects observed with QTc prologation out of them 3 subjects with Bipolar affective disorder, 4 subjects with Pneumonia, 1 Generalised anxiety disorder, one with panic attack and 1 with panic disorder observed with QTc prologation.Comparison of distribution of study subjects having prolonged QTc of different levels after medication results revealed that not significant (p=0.16) association with different gender group. Conclusion:The study concluded thatprolonged QTc of different levels after medication had not significant association with different gender group.Current guidelines by the American Heart Association recommend monitoring a baseline QTc before initiating any agent that may prolong the QTc interval.