Background: Chronic obstructive pulmonary disease (COPD) is a poorly reversible disease of the lungs that is one of the major causes of morbidity and mortality worldwide. An acute exacerbation of chronic obstructive pulmonary disease (AECOPD) is a clinical diagnosis made when a patient with COPD experiences a sustained (e.g., 24–48 h) increase in cough, sputum production, and/or dyspnea. Hence; the present study was conducted for assessing the profile of COPD patient admitted for acute exacerbation. Materials &Methods: A total of 100 subjects were enrolled in the present study. Inclusion criteria for the present study included subjects of more than 40 years of age and subjects with presence of AECOPD. Patients of AECOPD werethosewithincreaseinsputum quantity, needing hospital admission or a new prescription.Data was collected from eligible patients such as the age, gender, bodymassindexwerenoted.Smokerswere identified.Past medical historywasobtained.Sputum examination, chestX-rayandspirometryweredone. Results: Mean age of the patients was 53.3 years. Majority proportion of patients were males and were of urban residence. Cough, expectoration and breathlessness were seen in 100 percent of the patients while fever and chest pain were seen in 75 percent and 22 percent of the patients respectively. According to GOLD criteria, 15 percent, 56 percent, 20 percent and 9 percent of the patients were of GOLD criteria one, two, three and four respectively. Conclusion: Cough, shortness of breath and expectoration indicatedtheclinicalseverityofcases ofacuteexacerbationofCOPD.