Original Articles
Correlation study between serum uric acid and lipid profile in patients with essential hypertension | |
Dr. Devendra Nath Tiu, Dr. Deepayan Das | |
Background: Hypertension ranks among the most common chronic medical condition characterized by a persistent elevation in arterial pressure. Despite many theories of serum uric acid elevation, no solely reliable cause has been established, but it could be assumed that serum uric acid elevation is due to renal uric acid transport impairment. Hence; the present study was conducted for assessing the Correlation between serum uric acid and lipid profile in patients with essential hypertension. Materials & methods: A total of 100 patients with confirmed diagnosis of essential hypertension were enrolled. Complete demographic and clinical details of all the patients was obtained. All the patients were kept on overnight fasting and were recalled in the morning. Blood samples were taken and were sent to lab. Serum uric acid and lipid profile was evaluated using an auto-analyzer. All the results were recorded in Microsoft excel sheet and were subjected to statistical analysis using SPSS software. Results: Mean total cholesterol levels, mean HDL, mean LDL, mean triglycerides and mean uric acid levels were found to be 183.3 mg/dL, 43.9 mg/dL, 98.1 mg/dL, 161.7 mg/dL and 6.2 mg/dL respectively. Significant results were obtained while correlating serum uric acid levels with lipid profile among essential hypertension patients. Conclusion: It was shown that there is a strong correlation between uric acid and hypertension. Reducing the occurrence of hypertension may be possible by controlling hyper- and dyslipidemia with dietary modifications and medicines. |
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