Background: Dental implants have become an indispensable established therapy in dentistry in order to replace missing teeth in different clinical situations. When peri-implantitis prevalence is reported, the level of reporting must also be taken into consideration. Hence; the present study was conducted for assessing the incidence of peri-implantitis in a known population. Materials & methods: A total of 100 patients scheduled to undergo dental implant therapy for prosthetic rehabilitation of missing mandibular molar were enrolled. Complete demographic and clinical details of all the patients was obtained. Radiographic evaluation was done in all the patients. All the patients were screened with biochemical and hematological profile. Treatment planning was done based on radiographic analysis. All the patients underwent dental implant procedures using conventional technique. All the patients were recalled for follow-up. Follow-up records were maintained for 6 months to assess the incidence of peri-implantitis. Results: A total of 100 patients were analyzed. Mean age of the patients was 28.3 years. 65 percent of the patients were males while the remaining were females. Peri-implantitis was found to be present in 8 percent of the patients. Out of 8 patients with peri-implantitis, 5 were males while the remaining 3 were females. 3 patients were diabetic and 2 patients were found to be hypertensive. Conclusion: Biological problems do occur with implant therapy, even if it is acomprehensive course of care. Recalls for strict supportive care may result in early diagnosis and decreased incidence of peri-implantitis.