Aim: To evaluate the cytomorphological spectrum oflymph node lesions at a tertiary care hospital. Materials and method: A total of 100 cases of fine-needle cytology (FNC) of lymph nodes were examined at the Department of Pathology. The patients were provided with a detailed explanation of the procedure, and their consent was obtained. Using aseptic procedures, a 23-gauge needle and a 10 ml syringe were used to aspirate the lesion. Aspiration and non-aspiration techniques were used to extract a suitable amount of material. Slides were coated with the aspirate to create smears. According to the staining process, the smears were air dried or alcohol fixed to preserve them. Then, they were stained using H&E, PAP, Giemsa stain, and ZN stain to detect AFB. The FNAC diagnosis was correlated with pertinent clinical information and investigations.Results:Cervical lymphadenopathy (internal jugular chain & posterior triangle lymphadenopathy) was seen in 77 cases (77%) out of total 100 patients. Subsequently, submandibular lymphadenopathy was found in 8 cases (8%). The other sites of lymphadenopathy included supraclavicular in 5 cases(5%), axillary in 5 cases (5%), inguinal lymph nodes in 3 cases (3%), and the least prevalent location being submental with 2 cases (2%).The non-neoplastic lesions were more prevalent and diagnosed in 77 patients (77%), compared to neoplastic lesions in 23 cases (23%). Among non-neoplastic lesions, the most common diagnosis was non-specific reactive lymphadenitis, accounting for 39 cases (39%). Conclusion: Lymph node cytology is an effective and less invasive method for diagnosing lymphadenopathies. It aids in distinguishing between non-neoplastic and neoplastic etiology. Therefore, preventing unnecessary surgical procedures. FNAC, when paired with clinic-radiological correlation, may serve as the first diagnostic test for evaluating lymph node lesions.