Introduction: Osteoporosis is a skeletal disorder characterized by Low Bone Density and Micro architectural deterioration of bony tissue. This result in increased fracture risk. Most of the studies were done to identify Osteoporosis Prevalence in normal population in India and Worldwide. Our study was carried out to analyse the Prevalence of Osteoporosis and Osteopenia in disabled population. This is the first study in the World and also in India. As per the census 2011 in India out of 121 crore population, about 2.68 crore are disabled which is 2.21% of total population. Among the disabled population 56% are male and 44% are female.69% are disabled resided in rural area.Locomotor disability percentage in India is about 20%. Materials & Methods:The main purpose of this clinical study was to determine the prevalence of Osteoporosis and osteopenia in disabled people attending the free BMD camp conducted in Department Of Physical Medicine and Rehabilitation, Government Thiruvarur Medical College Hospital, Thiruvarur, TamilNadu in association with Department of Orthopaedics in Government medical colleges and compare the BMD (Bone Mineral Density) in relation to modifiable and non-modifiable risk factors by doing calcaneal Quantitative Ultra Sound Method. Results: Out of 142 cases 55% were Osteoporotic and 38% were Osteopenia and 7% were normal. In disabled with hypertension 90% were Osteoporotic and 10% were Osteopenia. In disabled with diabetes 100% were Osteoporotic. In post-polio Residual paralysis 86% were Osteoporotic and 14% were Osteopenic. In myopathy 90% were Osteoporotic and 10% were Osteopenic. In amputee 83.4% were Osteoporotic and 8.3% Investigate were Osteopenia and 8.3% were normal. In stroke 93% were Osteoporotic and 7% were Osteopenia. We found that 7% of disabled people were normal and 55% were osteoporotic and 38% were osteopenic. Conclusion: Affected peoples were advised to take calcium and vitamin D3 tablets and advised to do physical exercise and to follow dietary habits.