Background:Psoriasis is a chronic inflammatory skin disorder associated with various systemic comorbidities, including obesity and dyslipidemia. Understanding the prevalence and correlates of these metabolic abnormalities in individuals with psoriasis is essential for optimizing patient care.Methods:A hospital-based cross-sectional study was conducted among 270 individuals with psoriasis. Demographic data, disease characteristics, and comorbidities were assessed using structured questionnaires and clinical evaluations. Statistical analyses were performed to elucidate associations between psoriasis onset, disease duration, and metabolic abnormalities.Result:The study included 270 participants, with 61.9% males and 38.1% females. Obesity prevalence was higher in early onset psoriasis (20%) versus late onset (12.6%), with a significant difference (p = 0.048). Dyslipidemia was more prevalent in early onset (54.1%) compared to late onset (47.4%) cases, with a significant difference (p = 0.005). Diabetes mellitus prevalence was higher in late onset (31.1%) versus early onset (15.6%) psoriasis cases, showing significance (p = 0.003). Disease duration correlated with metabolic abnormalities, highlighting the importance of early intervention (p = 0.001).Conclusion:This study underscores the significant associations between psoriasis and metabolic abnormalities, emphasizing the need for comprehensive cardiovascular risk assessment and multidisciplinary care approaches in psoriasis management.