Original Articles
Evaluation of effectiveness of two different Doses of Clonidine as an Additive to Intrathecal Isobaric Levobupivacaine in Patients Undergoing Infraumbilical Surgeries: A comparative study | |
Dr. Mamta Sharma, Dr. Anil Sharma, Dr. Seema Raj Gupta, Dr. Surendra Kumar | |
Background: To compare two different doses of clonidine as an additive to intrathecal isobaric levobupivacaine in Patients Undergoing Infraumbilical Surgeries. Materials & methods:100 patients within the age range of 25 to 60 years were enrolled. Complete demographic and clinical details of all the patients was obtained. Inclusion criteria included patients of ASA grade I/II and schedule to undergo elective infraumbilical surgeries under spinal anesthesia. A total of two study groups were formed with 50 patients in each group as follows: Group A: Levobupivacaine 0.5% isobaric (3 mL) with clonidine 15 μg, & Group B: Levobupivacaine 0.5% isobaric (3 mL) with clonidine 30 μg. Patients receiving rescue analgesia who have a VAS score greater than 3. Hemodynamic variables were continuously monitored both during and after surgery. Every outcome was entered into a Microsoft Excel spreadsheet, and then SPSS software was used for statistical analysis. Results:Mean age of subjects of group A was 43.5 years and of subjects of group B was 41.9 years. Majority proportion of patients of both the study groups were males.Mean time of onset of sensory block among patients of group A and group B was 6.75 minutes and 3.12 minutes respectively; on comparing, significant results were obtained. Significant results were obtained while comparing the time for maximum sensory blockage and duration of analgesia among the two study groups. Conclusion:The addition of 30 μg of clonidine as an adjuvant could safely prolong the duration of postoperative analgesia in comparison to 15μg of clonidine. |
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