Background:Clinical staging refers to the assessment of cancer based on the information gathered before any treatment has been initiated.The present study was conducted to assess the impact of clinical versus pathological staging in oral cavity carcinoma. Materials & Methods:110 OSCC patients of both genders were enrolled. Parameters such as site, type of treatment done, etc. were recorded. Overall clinical and pathological TNM staging was compared and tabulated to determine upstaging, downstaging or cases where no stage discrepancy occurred. Results: Out of 110 patients, males were 68 and females were 42. The most common site was tongue border in 45, buccal mucosa in 32, labial mucosa in 21, retromolar area in 7, floor of mouth in 2, soft palate in 2, and hard palate in 1 patient. The difference was significant (P< 0.05). The highest congruence between clinical and pathological staging was seen for clinical stages 1 and 4 (32/55, and 3/5 respectively). Lower levels of correlation were seen for clinical stages 2 (16/28) and 3 (12/22). The level ofdisparity is largely attributed to upstaging, shown in 17%of clinically stage 2 patients and 422% of stage 3 patients. Conclusion: InSCC, there is some variation between clinical and pathological staging; nevertheless, this has no appreciable effect on disease-specific survival.