Aim:To study the clinical and epidemiological characteristics of sexually transmitted infection in patients visiting a specialized hospital. Material and methods: The collected data included the age, gender, residence, marital status, and socio-economic standing of the patients. For all patients, clinical information such as presenting problems, duration of symptoms, comparable concerns in partners, and any previous treatments were recorded. The diagnosis was established using a combination of patient history, clinical examination, and pertinent laboratory tests. Gram stain and potassium hydroxide (KOH) mount were performed on all urethral and vaginal discharge samples according to the data. Serological procedures, such as HIV antibody testing using enzyme-linked immunosorbent assay (ELISA) and rapid plasma regain test (RPR), were conducted on all patients. After diagnosing the patients, they were sent to a STI counselor for counseling. A positive RPR test result was verified using a Treponema pallidum haemagglutination (TPHA) test. STIs were classified based on different causative agents. Results: Vulvovaginal candidiasis was the most common (non-viral) STI observed in 80(40%) patients in our study followed by genital warts 17(8.5%), molluscum contagiosum 16(8%), gonococcal urithritis 16(8%), herpes genitalis 15(7.5%), chancroid 14(7%), bacterial vaginosis 12(6%), non-gonococcal urithritis 9(4.5%), genital scabies 7(3.5%), LGV 6(3%) and non-gonococcal cervicitis 5(2.5%). Conclusion: Our research found that fungal sexually transmitted infections (STIs) and viral STIs like as genital warts, molluscum contagiosum, and genital herpes are increasing gradually, whereas bacterial STIs are decreasing. This pattern aligns with findings from previous studies nationwide.