Aim: To determine the morphometric and volumetric measurements of the paranasal sinuses in the Indian population.Material and methods:This prospective cross-sectional research aimed to quantify structural variations of paranasal sinuses in individuals receiving CT scan examination. 210 participants took part in this research. We determined the volume of CT in each region by multiplying the area by the slice thickness. We used the Cavalieri principle to determine the total volume of regions by averaging the standard deviations of all slice volumes. Results:The mean volumes of the frontal sinus, maxillary sinus, ethmoid sinus, and sphenoid sinus were 8.41±1.34 cm3, 19.01±2.46 cm3, 7.34±1.04 cm3, and 7.11±1.21 cm3, respectively. There was a statistically significant difference in the volumes of paranasal sinuses across genders (P<0.05). The average capacity of paranasal sinuses in older persons gradually decreases. Patients with a straight nasal septum did not exhibit any statistically significant change in paranasal sinus volumes. The deviated nasal septum affected the size of certain paranasal sinuses. A statistically significant correlation has been shown in our investigation between the average volumes of paranasal sinuses and the existence of deviated nasal septum. Conclusion: We concluded that the computed tomography is a dependable technique for assessing various morphometric measurements and volumetric analysis of paranasal sinuses.