Background:The present study was undertaken for studying the profile of patients with acute STEMI. Materials & methods:A total of 100 patients were enrolled. All patients of acute ST elevation MI meeting inclusion criteria were enrolled in the study after obtaining informed written consent. Detailed clinical history, details of clinical examination, ECG changes and 2D Echo changes were recorded. Inclusion Criteria included patients from age above 18 years of age which fulfil the criteria of Acute STEMI. All the results were recorded in Microsoft excel sheet and were analysed by using SPSS software. Results:Mean age of the patients was 54.23 years. 81.69 percent of the patients were males while the remaining were females. Chest pain, Breathlessness and Palpitation were seen in 80 percent, 38 percent and 15 percent of the patients respectively. Edema, Raised JVP, Peripheral pulses not palpable, Xanthoma, Carotid bruit, Corneal arcus and Locomotor brachialis were seen in 5 percent, 3 percent, 5 percent, 8 percent, 7 percent, 14 percent and 3 percent of the patients respectively. LVEF was 20 ≥, 21 to 30, 31 to 40 and 41 to 50 in 6 percent, 5 percent, 8 percent, and 81 percent of the patients respectively. Conclusion:Chest pain was the most common presenting symptom. This demands the need of expansion of PCI service across different parts of country.