Background:Evaluation of correlation of lactate /albumin ratio in outcome of patients of sepsis in ICU.Materials & methods:50 patients admitted to ICU were subjected to detailed history and examination followed by investigations. Lactate/albumin ration was assessed.Results:Majority of the subjects belonged to the age range of 40 to 60 years. Mean age was found to be 49.7 years. 80 percent of the patients were males while the remaining were females. Mean lactate to albumin ratio was found to be 0.191. Mean serum prolactin levels were 9.74 among subjects with lactate/albumin ration of less than 0.15. Significant correlation was seen while associating lactate to albumin ratio with serum prolactin levels.Conclusion:Lactate/albumin ratio could be used as an independent predictor for the mortality among sepsis patients admitted to ICU.