Original Articles
Assessment of role of maternal serum ferritin as a predictive marker in intrauterine growth restriction | |
Dr. Swati, Dr. Indu Kumari | |
Background:The most frequent problem for both obstetricians and neonatologists is intrauterine growth restriction (IUGR). The present study was conducted to assess the role of maternal serum ferritin as a predictive marker in intrauterine growth restriction. Materials & Methods:82 antenatal women were selected and parameters such as period of gestation at delivery, mode of delivery, newborns' crown rump length, and birth weightwere measured.Neonates in group I were considered average for gestational age if their birth weight was greater than or equal to the 10th percentile for the corresponding gestational age. Babies in group II were considered tiny for gestational age if their birth weight was less than the 10th percentile for the matching gestational age.Maternal serum samples were taken at 25th week and again at 30-32 weeks in trace free mineral evacuated tubes for assessment of serum ferritin. Results: The mean age was 23.1years and 22.5years, mean hemoglobin was 10.2gm% and 11.6gm%, the period of gestation at delivery was 38.4 and 37.2, mean birth weight was 2653.1gm and 2174.2gm, mean ferritin level was 15.3ng/ml and 19.2ng/ml in group I and II respectively. The difference was significant (P< 0.05). There were 32 asymmetrically growth-restricted babies and 21 asymmetrically growth-restricted babies with serum ferritin value>20 ng/ml. There were 6 asymmetrically growth-restricted babies and 8 asymmetrically growth-restricted babies with serum ferritin value>20 ng/ml. There were 12 asymmetrically growth-restricted babies and 3 asymmetrically growth-restricted babies with serum ferritin value>20 ng/ml. The difference was significant (P< 0.05). Conclusion: There was a lack of association between maternal serum ferritin andintrauterine growth restriction.Further research is needed to determine the significance of maternal serum ferritin in differentiating between pregnancies with asymmetric IUGR and symptoms of placental insufficiency and those with simple small for gestational age newborns. |
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