Abstract Issue

Volume 11 Issue 2 (April-June) 2022

Original Articles

Assessment of the efficacy of NB-UVB, Goeckerman therapy, and the effect of the addition of retinoids to the treatment regimen in the treatment of psoriasis
Dr. Saurabh Agrawal

Background:Psoriasis is a chronic autoimmune skin disorder characterized by the rapid buildup of skin cells, leading to the formation of thick, scaly patches on the skin's surface. The present study was conducted to assess the efficacy of NB-UVB, Goeckerman therapy, and the effect of the addition of retinoids to the treatment regimen in the treatment of psoriasis. Materials & Methods:45 psoriasis patients of both genders were divided into 3 groups of 15 each. Group I were given NB-UVB, group II were treated with re-NB-UVB and group III with GOECKERMAN. Duration of disease (years), PASI score, treatment responses were recorded. Results: Group I had 8 males and 7 females, group II had 6 males and 9 females and group III had 7 males and 8 females. The mean disease duration was 8.4 years in group I, 9.5 years in group II and 11.3 years in group III. The mean PASI score was 11.2 in group I, 12.6 in group II and 13.7 in group III. The response was unresponsive (PASI - 75) in 10, 11 and 13 patients respectively. Conclusion: Goeckerman therapy found to be more effective as compared to NB-UVB phototherapy.Acitretin allowed for a decrease in UV exposure and improved efficacy, even though it did not affect treatment results in terms of PASI-75 responses when added to either NB-UVB or Goeckerman therapy.

 
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