Background: Acute pancreatitis remains a disorder with devasting consequences. Although most episodes are mild and self-limiting, up to one fifth of patient develop a severe attack that can be fatal. In spite of technical advances in medical and surgical field’s acute pancreatitis remains a major cause of morbidity and mortality. Severity of acute pancreatitis is linked to the presence of systemic organ dysfunction and/or necrotizing pancreatitis.Materials and Methods: This was a hospital based retrospective study which was conducted from July 2022 to December 2022 at tertiary care hospital, KRIMS, Karwar. All patients with a diagnosis of acute pancreatitis were included in this study in order to find out the clinical presentations from the available clinical, laboratory and radiological data. Results: Of the 50 patients in this study, 49 were male and 1 were female. Minimum age in our study was 18 years and maximum were 70 years. Maximum numbers of patients were below 45 years of age. Alcohol was identified as the most important etiological factor associated with acute pancreatitis. Among the known etiological factors 90% of the cases were related to alcoholism and 4% were due to gall stone disease. Abdominal pain and vomiting were the most common symptoms in our study. Epigastric tenderness was present in 96% of the cases and guarding/rigidity in 56% of cases. 16% patients showed jaundice as a sign of acute pancreatitis. There was no major difference between the CT grading system and clinical grading system. Most of the patients recovered with conservative treatment. Conclusion: Acute pancreatitis is one of the leading causes of increase in morbidity and mortality to society. Clinical assessment along with radiological findings correlated well with the morbidity and mortality. Our study identifies alcoholism as one of the most important etiological factors.