Introduction: The COVID-19 pandemic has influenced every aspect of healthcare and the general functioning of populations. In December 2019, emerging cases of a new strain of corona virus occurred in Wuhan, China, which spread across the globe within months. A few effects of COVID-19 have been overcrowded hospitals and intensive care units, a lack of hospital resources and nationwide lockdowns. Such factors have directly influenced the stroke treatment pathways established within primary care centres. Materials and methods: This study was conducted at Department of Emergency Medicine, Sri Siddartha Medical College and Research Centre, B.H Road, Agalkote, Tumkur, Karnataka, India, which is a tertiary-care, referral, teaching institute with a comprehensive stroke center and an efficient emergency department and critical care unit, in South India. This hospital receives patients from all socio-economic backgrounds, predominantly from central and southern districts of karnataka, India. Patients who present with stroke, are admitted to the emergency department. All patients are then evaluated by the on-call neurologist. Patients who are eligible for thrombolysis or mechanical thrombectomy are taken for the respective intervention and are then admitted to the intensive care unit (ICU) or the ward. Patients who do not fulfil eligibility criteria for emergent interventions are directly admitted to the ICU or ward, and managed by the neurology team. Results: The total number of patients admitted with stroke during the time period from March 2019 to May 2019, January 2020 to March 2020 and March 2020 to May 2020 were 41, 36 and 38 respectively. The total number of in-patient admissions and out-patient visits to the department of neurology, and the entire hospital are given in table 1. The demographic details of patients are given in Table 2. There were significantly lesser diabetic patients in the 2019 group (p value 0.03). Other characteristics were similar between the groups. Conclusion: The present study suggests that there may be a relative increase in the incidence of stroke in the community, as a result of the COVID-19 pandemic. The patients who presented with stroke during the lockdown period had a higher NIHSS score.