Background: Surgical site infection is one of the most common types of nosocomial infection encountered in surgical patients and a potential cause of mortality and morbidity adding to the economic burden of patients and hence it draws all the possible efforts for its prevention. Surgical site drains of various types are used at the end of various abdominal surgeries considering it’s therapeutic as well as diagnostic use. Drain can be a cause of surgical site infection too since it acts as a conduit for transporting outside infection to surgical site and being a foreign body causes inflammatory response in the body. Materials And Methods: This prospective observational study was conducted in a tertiary care medical college at Ludhiana, Punjab. Patients undergoing intra-abdominal surgeries were taken for this study. Patients with and without intra-abdominal drains were observed during post operative period on day 3, day 7, after one month and after three months for surgical site infections and detailed structured proforma was filled. Results: In this study we found that intra-abdominal drains are risk factor for surgical site infections in patients undergoing abdominal surgeries. In this study we observed the risk of surgical site infection to be 31.4%. Conclusion: The use of intra-abdominal drain is associated with surgical site infection. Drains kept in situ for longer duration, and a greater number of intra-abdominal drains increases the risk of SSI.