Background: liver is the biggest organ, is situated in the upper right region of the belly, extending into the middle and a tiny part of the upper left area. Couinaud's classification identifies eight distinct functional regions (I to VIII) within the liver. The split is based on how the portal vein system and the hepatic veins are distributed throughout the body.This study emphasises the anatomical arrangement of the hepatic artery and portal vein within the liver. Additionally, we discovered variations in the segmental supply, a topic that has received limited attention in prior studies of the Indian population. Purpose: This inquiry was conducted with the purpose of determining the gross anatomical differences of the liver as well as the consequences these variances have for clinical and surgical procedures. Methods: We examined the hepatic artery and portal vein's branching pattern using two methodologies: 1. “Luminal casting (modified) 2. Radiological study” A total of 20 liver specimens were utilised for luminal casting, with 10 specimens dedicated to studying the branching pattern of the hepatic artery and the other 10 specimens focused on examining the branching pattern of the portal vein.A total of 80 contrast-enhanced computed tomography (CECT) images were utilised for the radiological examination.Therefore, a sample size of 100 was utilised for each group.The acquired results were subsequently organised into a table. Statistical Analysis: Utilising the most recent version of SPSS, the appropriate statistical test was carried out. Results: Furthermore, the Indian population has rarely undergone detailed examination of the variations in segmental supply.Both the branching patterns of the portal vein and the hepatic artery are very uncommon to exhibit variations on the left side of the body. The branching pattern of the portal vein and the hepatic artery did not exhibit any noticeable differences regardless of the gender of the individual.