Aim: The aim of the present study was to evaluate the histopathological patterns identified on Transbronchial lung biopsy (TBLB) &Endobronchial Biopsy (EBB). Methods: The retrospective study was conducted for the period of 3 years and 125 consecutive bronchoscopic biopsies were included in the study. All bronchial biopsies were received in neutral buffered formalin, were processed as per standard procedure. 4-5 µm thick sections were cut on microtome and stained with Hematoxylin and Eosin (H&E) stain and the slides were studied in details microscopically. Special stains like Periodic Acid Schiff (PAS) and Ziehl–Neelsen (ZN) were used when needed. Results: Among 110 cases included in the study, 32 (29.10%) were female and 78 (70.90%) were male. The age range in the present study was 20 -78 years. The maximum number of patients was in the age group of 51-60 years and 61-70 years (40 each; 36.36%). Out of 102, 36 patients had chronic interstitial inflammation±Fibrosis followed by neoplasia in 20 patients. Out of 102 patients, 70 (68.6%) patients had contributory diagnostic yield. Conclusion: With availability of adequate material TBLBs & EBBs can provide useful diagnostic information (60.8% of cases in this study). Systematic categorisation of the histopathological patterns identified on TBLB helps to increase the diagnostic yield. Correlation with clinical and radiological features required for confirming the diagnosis accurately.