Background: Chronic obstructive pulmonary disease (COPD) is a common disease with pulmonary & extra-pulmonary symptoms. A mortality rate of 8.7% rate has been reported by Global Burden of Diseases, Injuries, and Risk Factors Study. It is a leading cause of mortality& disability. Aim and Objective: To study the effect of six minute walk test (6MWD) testin patients of COPD. Material and Methods: Present prospective, observational and comparative study was conducted on patients attended OPD/admitted in Dept. of Physical Medicine & Rehabilitation and Pulmonary Medicine of IPGME & R-SSKM Hospital, Kolkata over a period of 18 monthsinclinically diagnosed 70 cases (35 patients each in group A and B). Results: Mean age ofpatients in group A was 64.14±5.94 yearsand 65.05±5.58 inGroup B. 30 (75.72%) patients were male in Group A and 28(80%) patients in Group B. In Group A(82.85%)&Group B (77.15%) patientswere smoker. InGroup A statistically significantincrease in mean6MWDafter6 weeks & 12 weeks of PR(baseline 285.88±32.11 meter; 320.82±32.52 meter at 6 Wks; 345.48±32.10 meter at12Wks) was found. In group B, mean 6MWD increase wasnot statistically significant (baseline 296.34±28.17 meter ; 294.62±30.23 at 6 weeks & 297.02±28.89 at12 weeks). Conclusion: COPD patients had reduced exercise capacity (low 6 MWD)at baseline. Pulmonary rehabilitationresultsin statistically significant improvementin 6 MWT while no improvement was noted in the group not given pulmonary rehabilitation. Pulmonary rehabilitation found to be an effective non-pharmacological intervention for COPD patients. Results of the present study showed that pulmonary rehabilitation found to be an effective non-pharmacological intervention for COPD patients.