Aim: Comparative evaluation to assess and compare the surgical efficacy of ultrasonic surgery with conventional techniques in jaw cyst enucleation, to assess any complication associated with the use of piezosurgery and conventional surgical technique, to assess the bone healing and bone density using CBCT and to assess any postoperative complications. Materials and method:This study was conducted on 20 patients diagnosed with maxillary and/or mandibular cysts, aged between 15 and 65 years. Patients were randomly divided into two groups of 10 each. Group-A (n-10) Patients underwent cyst enucleation with piezosurgery, Group-B (n-10) Patients underwent enucleation by the conventional surgical technique. Results:Data was entered in Microsoft excel and Student T testand Chi-square test was analyzed by using statistical analysis software Graph pad Prism (Version 5), 80% of the patients were aged between 15 years and 30 years, 50% were male and 50% were female. Patients who were operated using a peizosurgey unit showed less post-operative pain reduced postoperative swelling and reduced trismus. However bone cutting was significantly faster in conventional surgery. Conclusion: To conclude there are certain pros and cons in using Piezo electric unit for the management of cysts of oral and maxillofacial region. From our study using we could derive the following advantages of using a piezo unit, less post operation pain, trismus and swelling, thereby, enabling a faster recovery of the patient, however the prominent drawback of using a piezo is the prolonged time spent on bone cutting thereby prolonging the duration of the surgery, the piezo tips are only effective in bone cutting and cannot be used in soft tissue procedures and lastly the piezo unit is expensive and can hamper its widespread use.