Background: The objective of this study is to assess the effectiveness and safety of using a low dose of vaginal misoprostol, specifically 25 µg, for the induction of labor. Labor induction is a critical medical intervention, often necessary for the well-being of both the mother and the fetus. The choice of medication and its dosage is crucial to ensure a smooth and successful induction process while minimizing potential risks. This research seeks to provide valuable insights into whether this lower dosage of misoprostol is a safe and effective option for labor induction, aiming to improve obstetric practices and maternal and fetal outcomes. Methods: In this study, 100 primigravida women were included and randomly divided into two groups. The first group received a low dose of 25 µg of misoprostol for cervical ripening and labor induction, while the second group served as the control, with no induction, allowing for the spontaneous progression of labor. The BISHOP prelabor scoring system was employed to evaluate the favorability of the cervix for labor induction, which considers various cervical parameters. Results: In this study, the majority of cases fell within the age group of 20-24 years, and most women in the case group had an unfavorable cervix with a Bishop Score of 6 or less. A significant difference was observed in the time it took for labor to begin actively between the two groups, with the induction group showing a notable advantage (p < 0.05). This finding suggests that low-dose misoprostol induction significantly reduced the time required for labor to progress into the active stage compared to allowing labor to initiate spontaneously. The study's results shed light on the potential benefits of using low-dose vaginal misoprostol for labor induction in primigravida women. Conclusion: Misoprostol has proven to be an effective agent for cervical priming and labor induction. However, it's important to note that its use may lead to a higher incidence of meconium-stained amniotic fluid, particularly in cases where the cervix is unfavorable. This increased incidence of meconium staining can have significant consequences, including a higher rate of cesarean deliveries due to concerns related to meconium-stained amniotic fluid