Aim: To investigate the impact of met for min, voglibose as individual interventions, and their combined effect on body mass index (BMI) in non-diabetic individuals with obesity. Material and Methods: The research included individuals of both sexes, aged between 20 and 58 years, who were classified as obese or overweight based on a body mass index (BMI) more than 25 kg/m2. Participants were required to express their willingness to take part in the study. metformin (500 mg) and voglibose 0.3mg tab were used. All the 90 patients were divided into 3 groups. Group A: Voglibose, Group B: Metformin and Group C: Combination (Voglibose+ Metformin). Results: The study observed a substantial difference in the comparison of voglibose and metformin within the same group at the beginning and after six months. However, the combination group (voglibose + metformin) showed an even more significant outcome. The intergroup comparison between the metformin and voglibose groups revealed no significant difference in BMI (0.57±0.04) when analysed using an unpaired t-test. The results were judged to be statistically non-significant, with a p-value greater than 0.05. A statistical analysis was conducted to evaluate the BMI between the Voglibose group and the combination group. The results of an unpaired t-test revealed a statistically significant difference in BMI (mean ± standard deviation: 1.86±0.78) between the two groups, with a p-value of less than 0.05 .The intergroup comparison between the metformin group and the combination group revealed a statistically significant difference in BMI (2.43±0.98) when analysed using an unpaired t-test. The p-value was determined to be less than 0.05, indicating statistical significance. Conclusion: We concluded that the Metformin 500mg BD alone, Voglibose 0.3mg BD alone, and a combination of Metformin 500mg with Voglibose 0.3mg BD, exhibited a statistically significant decrease in BMI values compared to their initial baseline measurements. Upon comparing the outcomes of the met for min group with the voglibose group, no statistically significant difference was seen.