Green plasma often poses a dilemma to transfusion medicine specialists as transfusion of such plasma units is questioned by many clinicians.So, mostly such plasma units are discarded at the blood bank itself. This is a case of a healthy 37-year-old male blood donor who donated whole blood (double bag 350 ml) at our blood bank after fulfilling all criteria of blood donation eligibility. During component preparation, plasma of this unit appeared greenish in colour. The plasma unit was quarantined and subjected to investigations such as culture, bilirubin (total, direct, and indirect), copper and ceruloplasmin assay and coagulogram profile. All investigations came out to be normal. Donor was called telephonically to check for any medical/surgical history which can cause the possible green discolouration of plasma but donor revealed no significant information. Despite of all normal findings, the plasma unit was discarded according to department policy. This case report highlights the importance of formulation of national guidelines in India regarding the fate of collected green/discoloured plasma to avoid unnecessary discard of blood components and to maintain uniformity in clinical practices.