Introduction: Diabetes mellitus is a common and serious disease with chronic complications and constitutes a substantial burden for both patients and the health care system. The latest estimates show a global prevalence of 382 million people with diabetes in 2013. In 2014, 8.5% of adults aged 18 years and older had diabetes, expected to rise to 592 million by 2035 [1]. In2019,diabeteswasthedirectcauseof1.5milliondeaths. Aim: assessing the prevalence and to study the clinical profile of macrovascular complications in newly diagnosed T2DM patients. Method: The present study was a single-center, cross-sectional study conducted on patients with newly detected T2DM in the department of General Medicine, Dr. B. R. Ambedkar Medical College, Kadugondanahalli, and Bangalore from November 2020 to May 2022(18 months) . Results: In this present study, 56 % and 44% comprised males and females respectively and male: female ratio was 1.2:1. Body mass index is a profound parameter for the onset of diabetes and its complications. Study results showed that (3%) were malnourished, (52%) were normal, (23%) overweight,(22%) were obese grade 1,(and 7%) were obese grade 2. Macroscopic complications include 38.7%, 32.7%, 27.3% , polyuria, polydipsia and polyphagia, respectively. Conclusion: In our study, the prevalence of diabetes rises with age and the predominance ofmale participants.