Background:One of the most frequent presenting ailments of children seen in Pediatric emergency is fever. The present study was conducted to evaluate serious bacterial infections (SBI)in children. Materials & Methods:74 children having serious bacterial infections (SBI)of both genders was included and clinical profile of each patient was recorded. Results: Out of 74 children, males were 44 and females were 30. Common diagnosis was enteric fever in 12, bacterial meningitis in 3, bronchiolitis in 12, dysentery in 8, upper respiratory tract infection in 7 patients, bronchopneumonia in 6, urinary tract infection in 4 and severe acute malnutrition in 22 cases. The difference was significant (P< 0.05). Conclusion: In children common bacterial infection found was bronchopneumonia, urinary tract infection, severe acute malnutrition, enteric fever, bacterial meningitis and bronchiolitis.