Background: Shivering is a prevalent perioperative complication that arises due to the occurrence of postanesthesia hypothermia. The objective of this current randomized clinical trial was to assess and compare the effectiveness of intravenous tramadol and intravenous dexmedetomidine in the prevention of post-anaesthesia shivering. Material & Methods:A total of 80 adult patients with ASA status I and II were randomly allocated into two groups. Group A consisted of 40 patients who received dexmedetomidine, while Group B consisted of 40 patients who received tramadol. The attending anesthesiologist would document the following information: the onset time of shivering following spinal anesthesia, the severity of the shivering, the rate of response to treatment, and the duration until the shivering subsided. The data were presented as the mean ± standard deviation (SD) or as a percentage. A significance level of p < 0.05 was deemed to indicate statistical significance. A p-value less than 0.001 was deemed to be highly significant. Results:In the current study, Group A consisted of 24 male patients and 16 female patients, while Group B comprised 21 male patients and 19 female patients. The average age of patients in group A was 48.76 years, while in group B it was 65.45 years. In group A, there were a total of 40 patients, with 20 classified as ASA grade I and 20 classified as ASA grade II. In group B, there were a total of 40 patients, with 15 classified as ASA grade I and 25 classified as ASA grade II.The duration of surgery in group A was recorded as 76.48 minutes, while in group B, it was observed to be 120.54minutes.The duration of spinal surgery in group A was recorded as 80.78 minutes, while in group B it was observed to be 130.29 minutes. There were no statistically significant differences observed between the two groups in terms of the time it took for shivering to begin, the intensity of shivering, and the time at which shivering recurred. The average duration from drug administration (dexmedetomidine and tramadol) to the point at which shivering completely stopped was significantly shorter in the dexmedetomidine group. Conclusion:The study's findings indicated that the average duration from the administration of dexmedetomidine and tramadol to the complete cessation of shivering was significantly shorter in the group receiving dexmedetomidine.